The role of Fluorine-18-Fluorodeoxyglucose positron emission tomography in staging and restaging of patients with osteosarcoma
Aim: The objective of this study is to systematically review the role of positron emission tomography (PET) and PET/computed tomography (PET/CT) with Fluorine-18-Fluorodeoxyglucose (FDG) in patients with osteosarcoma (OS). Methods: A comprehensive literature search of published studies through October 10th, 2012 in PubMed/MEDLINE, Embase and Scopus databases regarding whole-body FDG-PET and FDG-PET/CT in patients with OS was performed. Results: We identified 13 studies including 289 patients with OS. The main findings of these studies are presented. Conclusion: The combination of FDG-PET or FDG-PET/CT with conventional imaging methods seems to be a valuable tool for the staging and restaging of patients with OS and has a relevant impact on the treatment planning.