Recurrence rate in regional lymph nodes in 737 patients with follicular or Hürthle cell neoplasms

  • Andrej Vogrin
  • Hana Besic
  • Nikola Besic
  • Maja Marolt Music

Abstract

Background. Preoperative ultrasound (US) evaluation of central and lateral neck compartments is recommended for all patients undergoing a thyroidectomy for malignant or suspicious for malignancy cytologic or molecular findings. Our aim was to find out how frequent was recurrence in regional lymph nodes in patients with follicular or Hürthle cell neoplasm and usefulness of preoperative neck US investigation in patients with neoplasm.

Patients and Methods. Altogether 737 patients were surgically treated because of follicular or Hürthle cell neoplasms from 1995 to 2014 at our cancer comprehensive center. Altogether 207 patients (163 females, 44 males; mean age 52 years) had thyroid carcinoma.

Results. Carcinoma was diagnosed in follicular and Hürthle cell neoplasm in 143/428 and 64/309 of cases, respectively. A recurrence in regional lymph nodes occurred in 12/207 patients (6%) during a median follow-up of 55 months. Among patients with carcinoma a recurrence in regional lymph nodes was diagnosed in follicular and Hürthle cell neoplasms in 2% and 14%, respectively (p=0.002). Recurrence in regional lymph nodes was diagnosed in 3/428 (0.7%) of all patients with follicular neoplasm and 9/309 (3%) of all patients with Hürthle cell neoplasm.

Conclusions. Preoperative neck ultrasound examination in patients with a follicular or Hürthle cell neoplasm is probably not useful. Recurrence in lymph nodes was diagnosed in 0.7% of patients with a preoperative diagnosis of follicular neoplasm and 3% of patients with a Hürthle cell neoplasm. A recurrence in regional lymph nodes is rare in patients with carcinoma and preoperative diagnosis of follicular neoplasm.

Keywords: Thyroid Neoplasms, Ultrasonography, Recurrence, Diagnosis, Pathology

Published
2016-08-30
How to Cite
Vogrin, A., Besic, H., Besic, N., & Marolt Music, M. (2016). Recurrence rate in regional lymph nodes in 737 patients with follicular or Hürthle cell neoplasms. Radiology and Oncology, 50(3). Retrieved from https://radioloncol.com/index.php/ro/article/view/2494
Section
Clinical oncology