MRI Prognostic Factors of Tongue Cancer (Tumor Thickness, Para-lingual Distance & DWI/ADC Values): Potential Predictors of Cervical Lymph Nodal Metastases
Abstract
Abstract (Eng)
Purpose: This study aimed to evaluate the efficacy of three MR imaging parameters which are tumour thickness, para-lingual distance and ADC values for prediction of cervical lymph nodal metastasis in cancer tongue patients.
Methods: Fifty patients with known cancer tongue by histopathological examination underwent MRI examination. T1 and T2- weighted MRI, Diffusion-weighted images and post-contrast T1 fat suppression sequences were used.
Results: The patients were classified according to LN involvement as seen by MRI into two groups. Significant differences between positive and negative nodal groups were observed regarding tumour thickness and para-lingual distance (p values = 0.008 and 0.003 respectively). ROC curve analyses revealed cut off values >13.8 mm and ≤ 3.3 mm for tumour thickness and para-lingual distance respectively for prediction of positive nodal spread. No significant differences between patients with and without cervical lymph nodal metastasis regarding corresponding ADC values of the tumor (p-value = 0.518).
Conclusion: Para-lingual distance and tumor thickness are significant factors that could influence pre-operative judgment and prognosis of tongue cancer patients. ADC value of the tumour itself did not seem to be a reliable index to the stage of cancer progression or prediction of the status of lymph nodal spread.
Keywords: Tongue cancer, tumor thickness, para-lingual distance, apparent diffusion coefficient, cervical lymph node metastases.
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Radiology and Oncology (ISSN 1318-2099) is a multidisciplinary journal devoted to-the publishing of original and high quality articles in diagnostic and interventional radiology, computerized tomography, ultrasound, magnetic resonance, nuclear medicine, radiotherapy, clinical and experimental oncology, radiobiology, radiophysics, and radiation protection. Therefore, the scope of the journal is to cover beside radiology diagnostic and therapeutic aspects in oncology, which distinguishes it from other journals in the field.
Open access on the web: ISSN 1518-3207 Versita Open Radiology and Onkology
