MRI Prognostic Factors of Tongue Cancer (Tumor Thickness, Para-lingual Distance & DWI/ADC Values): Potential Predictors of Cervical Lymph Nodal Metastases

  • Mohamed A.F. Mourad Minia University, Egypt
  • Mahmoud M. Higazi Minia University, Egypt

Abstract

Abstract (Eng)

Purpose: This study aimed to evaluate the efficacy of three MR imaging parameters which are tumour thickness, para-lingual distance and ADC values for prediction of cervical lymph nodal metastasis in cancer tongue patients.

Methods: Fifty patients with known cancer tongue by histopathological examination underwent MRI examination. T1 and T2- weighted MRI, Diffusion-weighted images and post-contrast T1 fat suppression sequences were used.

Results: The patients were classified according to LN involvement as seen by MRI into two groups. Significant differences between positive and negative nodal groups were observed regarding tumour thickness and para-lingual distance (p values = 0.008 and 0.003 respectively). ROC curve analyses revealed cut off values >13.8 mm and ≤ 3.3 mm for tumour thickness and para-lingual distance respectively for prediction of positive nodal spread. No significant differences between patients with and without cervical lymph nodal metastasis regarding corresponding ADC values of the tumor (p-value = 0.518).

Conclusion: Para-lingual distance and tumor thickness are significant factors that could influence pre-operative judgment and prognosis of tongue cancer patients. ADC value of the tumour itself did not seem to be a reliable index to the stage of cancer progression or prediction of the status of lymph nodal spread. 

Keywords: Tongue cancer, tumor thickness, para-lingual distance, apparent diffusion coefficient, cervical lymph node metastases.

Author Biographies

Mohamed A.F. Mourad, Minia University, Egypt

Lecturer at Radiology Department

Minia University Faculty of Medicine, Egypt

Mahmoud M. Higazi, Minia University, Egypt

Lecturer at Radiology Department

Minia University Faculty of Medicine, Egypt

Published
2019-02-21
How to Cite
Mourad, M., & Higazi, M. (2019). MRI Prognostic Factors of Tongue Cancer (Tumor Thickness, Para-lingual Distance & DWI/ADC Values): Potential Predictors of Cervical Lymph Nodal Metastases. Radiology and Oncology, 53(1). Retrieved from https://radioloncol.com/index.php/ro/article/view/3170
Section
Radiology