Health-related quality of life in Slovene patients with colorectal cancer: a single tertiary care centre study
Aim. The aim of our study was to evaluate the influence of the surgical treatment on the Slovenian colorectal cancer patient's health-related quality of life and to compare the results to the health-related quality of life of the general Slovenian population.
Methods. 413 patients with colorectal cancer, who were operated on at the Department of the Abdominal surgery at the University Medical Centre Ljubljana between 01.01.2016 and 31.12.2017 were sent two standardized and validated questionnaires: EORTC QLQ-C30 version 3 and EORTC QLQ-CR29. 197 patients returned the questionnaires.
Results. Compared to the general population, poorer physical (p < 0.001), role (p = 0.002), cognitive (p = 0.021) and social functioning (p < 0.001) with higher frequency of constipation (p < 0.001), diarrhoea (p < 0.001) and financial difficulties (p < 0.001) were reported among colorectal patients. Female patients reported lower cognitive (p = 0.034) and emotional (p = 0.008) functioning, as well as a higher frequency of bloating (p = 0.049) and hair loss (p=0.01). Compared to the younger group of patients, a lower physical functioning (p < 0.001), higher urinary frequency (p = 0.007), urinary incontinence (p = 0.007), buttock pain (p = 0.007) and anxiety regarding body weight (p = 0.031) were detected among the older group of colorectal patients.
Conclusions. Global health status of colorectal patients in Slovenia is comparable to the one of the general Slovenian population, but there is a significant decrease in some of the scales of quality of life.
Key words:Health-related quality of life; colorectal cancer; colorectal surgery; Slovenia.