Treatment modalities for endometrial cancer

Abstract

Background. Endometrial cancer represents a high health burden in Slovenia and worldwide. The incidence is increasing due to risk factors of lifestyle and behavior such as obesity, smoking, estrogen exposure and aging of the population. In many cases, endometrial cancer is diagnosed at an early stage due to obvious signs and symptoms. The standard treatment is surgery with or without adjuvant therapy, depending on the stage of the disease and the risk of recurrence. However, the treatment modalities have changed in recent decades, considerably in the extent of lymphadenectomy.

Conclusions. The gold standard of treatment of EC is surgery, which can be an only treatment modality in the early stages low grade tumours. In recent years, a minimally invasive approach with SNB has been proposed. If EC is in advance stage, high-risk hystology or high grade,  adjuvant therapy is recomended, radiotherapy, chemotherapy or a combination of both is recommended.

Key words: endometrial cancer, uterus, treatment, minimally invasive surgery, laparoscopy