Cardiac myxoma: single tertiary centre experience


  • Polona Kačar a. Department of Cardiology, University Medical Center Ljubljana
  • Nejc Pavšič a. Department of Cardiology, University Medical Center Ljubljana
  • Mojca Bervar a. Department of Cardiology, University Medical Center Ljubljana
  • Zvezdana Dolenc Stražar Institute of Pathology, Faculty of Medicine, University of Ljubljana
  • Vesna Zadnik d. Epidemiology and Cancer Registry, Institute of Oncology Ljubljana
  • Matija Jelenc e. Department of Cardiovascular Surgery, University Medical Center Ljubljana
  • Katja Prokšelj University Medical Centre Ljubljana



Although cardiac myxoma (CM) are rare and benign, they can cause life-threatening complications, such as hemodynamic disturbances or embolization. Surgical excision of the tumor is the treatment of choice.


The aim of our study was to evaluate the epidemiological characteristics, clinical presentation, imaging findings, and outcomes of surgical treatment of patients with CM treated in the largest tertiary care centre in Slovenia.

Methods and results

We retrospectively analyzed the medical records of all patients referred to our institution between January 2005 and December 2020 and identified 39 consecutive adult patients with pathologically confirmed CM. The average annual incidence of CM in our study was 3 per 2 million population per year. Patients were more often female (n=25, 64%). The mean age at diagnosis was 63.1±13.6 years. Dyspnea was the most common presenting symptom (31%). CM was an incidental finding in 11 patients (28%). Seven patients presented with thromboembolic event (18%). Transthoracic echocardiography (TTE) was performed in all patients, however additional imaging was required in 22 patients (56%). All patients in our series were successfully treated surgically without in-hospital mortality. During the follow-up period (6 months to 16 years) three patients (8%) died, and all deaths were unrelated to CM. There was no recurrence of CM during the follow-up.


Our single-centre study confirms that CM is rare cardiac tumor with diverse clinical presentation. Our data shows data that CM might be more prevalent than considered before. Surgical resection of the tumor is safe with excellent short- and long-term outcomes.




How to Cite

Kačar, P., Pavšič, N., Bervar, M., Dolenc Stražar, Z., Zadnik, V., Jelenc, M., & Prokšelj, K. (2022). Cardiac myxoma: single tertiary centre experience. Radiology and Oncology, 56(4), 535–540. Retrieved from



Clinical oncology