ENDOSCOPIC MANAGEMENT FOR COLORECTAL OB-STRUCTION CAUSED BY ADVANCED AND UNRESEC-TABLE CANCER: ELETTROCHEMOTHERAPY AS TREATMENT SOLUTIONSBACKGROUND: Electrochemotherapy (ECT) is a minimally invasive and safe treatment gaining posi-tive and long-lasting an
BACKGROUND: Electrochemotherapy (ECT) is a minimally invasive and safe treatment gaining positive and long-lasting anti-tumoral results that is getting the attention of the scientific community. It is a local treatment that combines the use of electroporation and the administration of cytotoxic drugs in order to induce cell necrosis in the target tissue.
ECT is largely used for treatment of cutaneous and subcutaneous lesions and good results have been reported for treatment in deep visceral tumours. This article describes a novel approach of ECT: endoscopic treatment of colorectal cancer. Endoscopic ECT application was combined to systemic chemotherapy in the treatment of an obstructing rectal cancer without surgery prospective. A good response after ECT was described: concentrical involvement of rectum was reduced, no stenosing lesions were detective.
CONCLUSIONS: Endoscopic treatment for gastrointestinal cancer is a innovative application of ECT. Combination of systemic treatment and ECT resulted safe and highly effective in treatment of colorectal cancer, especially when obstructive, giving the patient a significative gain in quality of life.
How to Cite
Copyright (c) 2022 Radiology and Oncology
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
License to Publish
Please read the terms of this agreement, print, initial page 1, sign page 3, scan and send the document as one file attached to an e-mail to email@example.com